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The best serums with salicylic acid

salicylic acid
acne
serums

Last updated: 2/25/2025

/ Published: 2/12/2025

Serums with salicylic acid: what it is used for, properties and what products we recommend

Caring for acne-prone skin requires specific products that not only treat blemishes, but are also gentle on sensitive skin. Below, we reveal which are the best serums with salicylic acid.

What is salicylic acid and what is it used for?

Salicylic acid is an organic compound belonging to the beta-hydroxy acid (BHA) family and is found naturally in willow bark, from which it takes its name (Salix in Latin). It is one of the most recommended active ingredients for acne-prone skin thanks to its ability to gently exfoliate, unclog pores and reduce inflammation.

Properties of salicylic acid

Widely used in dermatology and cosmetics for its many skin benefits, the properties of salicylic acid are as follows:

  • Its exfoliating action helps to remove dead skin cells from the skin’s surface.
  • Its anti-inflammatory properties help to reduce both inflammation and redness.
  • It helps to unclog pores, preventing the formation of blackheads and whiteheads.
  • By reducing sebum production, it is ideal for oily and/or acne-prone skin.
  • It has antifungal and antimicrobial properties.

Products with salicylic acid: the best serums

Now that you know the properties of this active ingredient, here is our selection of the best serums with salicylic acid for acne-prone skin.

Biretix Doble Corrección Sérum

This sérum de Biretix is one of our recommended products for acne-prone skin care. It contains salicylic acid combined with retinoids and niacinamide, giving it an exfoliating, anti-inflammatory and sebum-regulating action that helps reduce breakouts and improve skin texture. It can also be applied both morning and night.

Effaclar Sérum de La Roche-Posay

With a unique combination of salicylic acid, LHA (lipo-hydroxy acid) and glycolic acid, the sérum Effaclar de La Roche-Posay is perfect for oily, acne-prone skin. Its exfoliating action helps to refine pores, preventing the appearance of new blemishes. And that is not all, as its gentle formula is suitable even for sensitive skin.

Ducray Keracnyl Sérum

The sérum Keracnyl de Ducray is an exceptional option for those looking for an effective solution against acne. In addition to salicylic acid, it contains Myrtacine extract, which fights the bacteria responsible for acne. What is more, this serum not only helps to reduce blemishes, but also improves residual marks, making it ideal for those affected by acne marks.

Eucerin Dermopure Oil Control Sérum Triple Efecto

This sérum Oil Control de Eucerin is an excellent option thanks to its triple effect: on the one hand it regulates sebum, and on the other, it exfoliates and reduces acne marks. Among its active ingredients, salicylic acid works by unclogging pores, while Licochalcone A soothes irritation. Perfect for night-time use, it will help improve the appearance of acne-prone skin.

How often should you use salicylic acid?

Using salicylic acid on acne-prone skin depends on several factors, such as the type of product, since, for example, the serums mentioned above are for daily use. However, it is worth bearing in mind that there are other products with salicylic acid for which gradual application is recommended, starting with a frequency of 1 to 2 times per week. As the skin becomes accustomed to it, the frequency of use can be increased.

As you can see, caring for acne-prone skin does not have to be complicated if you choose the right products. Remember that if you have any questions or would like more recommendations, you can speak to our team of expert pharmacists.

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