Combix Efg Dexketoprofen 25 mg, 12 film-coated tablets

Dexketoprofen Combix tablets is an analgesic belonging to the group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat mild to moderate pain, such as muscle or joint pain, menstrual pain (dysmenorrhoea), dental pain.

Adults over 18 years of age.

The dose of Dexketoprofen Combix that you need may vary, depending on the type, intensity and duration of the pain. Your doctor will tell you how many tablets to take per day and for how long.

In general, 1 tablet (25 mg dexketoprofen) every 8 hours is recommended, not exceeding 3 tablets a day (75 mg).

If you are elderly or have kidney or liver disease, it is recommended to start therapy with a maximum of 2 tablets per day (50 mg).

In elderly patients, this initial dose may be subsequently increased according to the general recommended dose (75 mg dexketoprofen) if Dexketoprofen Combix has been well tolerated.

If your pain is severe and you need quick relief, take the tablets on an empty stomach (at least 30 minutes before a meal) as they will be more easily absorbed.

• If you are allergic to dexketoprofen trometamol or any of the other ingredients of this medicine.
• If you are allergic to acetylsalicylic acid or any other non-steroidal anti-inflammatory drug.
• If you have asthma or have had asthma attacks, acute allergic rhinitis, nasal polyps, hives, angioedema or wheezing in the chest after taking aspirin or other non-steroidal anti-inflammatory medicines.
• If you have or have had in the past peptic ulcer, stomach or intestinal bleeding or have chronic digestive problems.
• If you have had stomach or intestinal bleeding or perforation in the past due to previous use of non-steroidal anti-inflammatory drugs (NSAIDs) used for pain.
• If you have chronic inflammatory bowel disease (Crohn's disease or ulcerative colitis).
• If you have severe heart failure, moderate to severe kidney failure or severe liver failure.
• If you have bleeding disorders or blood clotting disorders.
• If you are pregnant or breast-feeding.
• If you are under 18 years of age.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The possible side effects are listed below according to their frequency. The following table indicates how many patients may experience these side effects:

• Frequent: More than one in 100 people and less than one in 10.
• Infrequent: More than one in 1,000 people and less than one in 100.
• Rare: More than one in 10,000 people and less than one in 1,000.
• Very rare: Less than one in 10,000 people, including isolated cases.

Common side effects: Nausea and/or vomiting, stomach pain, diarrhoea, digestive disorders (dyspepsia).

Rare side effects: Rotatory sensation (vertigo), dizziness, drowsiness, sleep disorders, nervousness, headache, palpitations, hot flushes, stomach problems, constipation, dry mouth, flatulence, skin rash, fatigue, pain, feverish sensation and chills, general malaise.

• If you are allergic or have had allergy problems in the past.
• If you have kidney, liver or heart disease (hypertension and/or heart failure), or fluid retention or have suffered from any of these diseases in the past.
• If you are taking diuretics or have insufficient hydration and reduced blood volume due to excessive fluid loss.
• If you have heart problems, a history of stroke, or think you may be at risk for these conditions.
• If you are elderly you may have a higher incidence of side effects. If these occur, consult your doctor immediately.
• If you are a woman with fertility problems (Dexketoprofen Combix may decrease your fertility so you should not take it if you are planning to become pregnant or if you are undergoing fertility tests).
• If you have a blood and blood cell production disorder.
• If you have systemic lupus erythematosus or mixed connective tissue disease.
• If you have or have had in the past chronic inflammatory bowel disease (ulcerative colitis, Crohn's disease).
• If you are taking other medicines that increase the risk of peptic ulcer or bleeding.

The active substance is dexketoprofen trometamol (36.90 mg) corresponding to 25 mg dexketoprofen (INN).

The other ingredients are: maize starch, pregelatinised maize starch, microcrystalline cellulose, hydroxypropylcellulose, magnesium stearate, white opadry (hypromellose, titanium dioxide and macrogol 400).

• Do not take a double dose to make up for a forgotten dose.

The price of non-prescription medicines is set by law. However, at Farmaciasdirect you can buy Combix Efg Dexketoprofen 25 Mg, 12 coated tablets at a discount of up to 10%, which is the legal maximum allowed.