Before the first application, the animal should be meticulously brushed or combed to remove as many loose hairs as possible. Then, moisten a cloth with Vetriderm Topical Lotion and carefully rub the animal's skin. The application should be made following the direction of the hair, then in the opposite direction, without forgetting the abdominal and genital area. The cloth should be moistened, but not too much. Normally, one application per week is sufficient to effectively control the amount of dirt. It is advisable that the first application of the product should not be carried out by allergic persons, as organic remains such as epithelium, saliva and urine can trigger allergic reactions. However, subsequent treatments can be carried out by allergic persons in most cases.